The article "Binance Research: How DeSci Reimagines Science from Challenges to Opportunities" (compiled by Will Awang) points out that traditional scientific research faces a "valley of death" phenomenon when transitioning from basic research to practical applications, such as 80% -90% of research projects failing before human trials due to insufficient funding caused by inconsistent incentive mechanisms, reduced collaboration between researchers and clinical doctors, and poor reproducibility and replicability of scientific discoveries. DeSci utilizes the Web3 stack DAO、 Blockchain and smart contracts address these challenges, such as coordinating stakeholders to solve funding issues through DAO, promoting collaboration between researchers and clinical doctors, and utilizing blockchain to record experiments to improve replicability and reproducibility. The DeSci landscape covers four key innovation areas: infrastructure, research, data services, and Memes, with many sub industries having great potential for development. Although DeSci is still in its early stages and the existing technology stack is not very suitable for clinical research, the legitimacy of DAO is controversial. However, it has been able to influence scientific research methods, and solving the "valley of death" problem is an important progress. https://www. (wublock123.com)/index.php? m=content&c=index&a=show&catid=47&id=37922